Week 6: Neurologic and Musculoskeletal Disorders and Opioids
Sabrina is a 26 year old female who has just been diagnosed with multiple sclerosis. She has scheduled an appointment for a follow up with her physician but has several questions about her diagnosis and is calling the Nurse Helpline for her hospital network. As she talks with the advanced practice nurse, she learns that her diagnosis also impacts her neurologic and musculoskeletal systems. Although multiple sclerosis is an autoimmune disorder, both the neurologic and musculoskeletal systems will be affected by adverse symptoms that Sabrina needs to be aware of and for which specific drug therapy plans and other treatment options need to be decided on.
As an advanced practice nurse, what types of drugs will best address potential neurologic and musculoskeletal symptoms Sabrina might experience?
This week, you will evaluate patients for the treatment of neurologic and musculoskeletal disorders by focusing on specific patient case studies through a decision tree exercise. You will analyze the decisions you will make in the decision tree exercise and reflect on your experiences in proposing the recommended actions to address the health needs in the patient case study.
Required Readings (click to expand/reduce)
Rosenthal, L. D., & Burchum, J. R. (2021). Lehneâ€™s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.
Â· Chapter 11, â€œBasic Principles of Neuropharmacologyâ€ (pp. 67â€“71)
Â· Chapter 12, â€œPhysiology of the Peripheral Nervous Systemâ€ (pp. 72â€“81)
Â· Chapter 12, â€œMuscarinic Agonists and Cholinesterase Inhibitorsâ€ (pp. 82â€“89)
Â· Chapter 14, â€œMuscarinic Antagonistsâ€ (pp. 90-98)
Â· Chapter 15, â€œAdrenergic Agonistsâ€ (pp. 99â€“107)
Â· Chapter 16, â€œAdrenergic Antagonistsâ€ (pp. 108â€“119)
Â· Chapter 17, â€œIndirect-Acting Antiadrenergic Agentsâ€ (pp. 120â€“124)
Â· Chapter 18, â€œIntroduction to Central Nervous System Pharmacologyâ€ (pp. 125â€“126)
Â· Chapter 19, â€œDrugs for Parkinson Diseaseâ€ (pp. 127â€“142)
Â· Chapter 20, â€œDrugs for Alzheimer Diseaseâ€ (pp. 159â€“166)
Â· Chapter 21, â€œDrugs for Seizure Disordersâ€ (pp. 150â€“170)
Â· Chapter 22, â€œDrugs for Muscle Spasm and Spasticityâ€ (pp. 171â€“178)
Â· Chapter 24, â€œOpioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesicsâ€ (pp. 183â€“194)
Â· Chapter 59, â€œDrug Therapy of Rheumatoid Arthritisâ€ (pp. 513â€“527)
Â· Chapter 60, â€œDrug Therapy of Goutâ€ (pp. 528â€“536)
Â· Chapter 61, â€œDrugs Affecting Calcium Levels and Bone Mineralizationâ€ (pp. 537â€“556)
American Academy of Family Physicians. (2019). Dementia. Retrieved from http://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=5
This website provides information relating to the diagnosis, treatment, and patient education of dementia. It also presents information on complications and special cases of dementia.
Linn, B. S., Mahvan, T., Smith, B. E. Y., Oung, A. B., Aschenbrenner, H., & Berg, J. M. (2020). Tips and tools for safe opioid prescribing: This review–with tables summarizing opioid options, dosing considerations, and recommendations for tapering–will help you provide rigorous Tx for noncancer pain while ensuring patient safety. Journal of Family Practice, 69(6), 280â€“292.
Required Media (click to expand/reduce)
Laureate Education (Producer). (2019b). Alzheimerâ€™s disease [Interactive media file]. Baltimore, MD: Author.
In this interactive media piece, you will engage in a set of decisions for prescribing and recommending pharmacotherapeutics to treat Alzheimerâ€™s disease.
Laureate Education (Producer). (2019e). Complex regional pain disorder [Interactive media file]. Baltimore, MD: Author.
In this interactive media piece, you will engage in a set of decisions for prescribing and recommending pharmacotherapeutics to treat complex regional pain disorders.
Disorders of The Nervous System
Reflect on the comprehensive review of disorders of the nervous system and think about how you might recommend or prescribe pharmacotherapeutics to treat these disorders. (15m)
Accessible player –Downloads– Download Video w/CC Download Audio Download Transcript
Speed Pharmacology. (2019). Drugs for Parkinsonâ€™s Disease (Made Easy) [Video]. https://www.youtube.com/watch?v=Z84iypHdftQ&t=13s Note: This media program is approximately 9 minutes.
Speed Pharmacology. (2019). Pharmacology- Drugs for Alzheimer’s Disease (Made Easy) [Video]. https://www.youtube.com/watch?v=euzRPrvrwj0&t=31s Note: This media program is approximately 7 minutes.
Assignment: Decision Tree for Neurological and Musculoskeletal Disorders
For your Assignment, your Instructor will assign you one of the decision tree interactive media pieces provided in the Resources. As you examine the patient case studies in this moduleâ€™s Resources, consider how you might assess and treat patients presenting symptoms of neurological and musculoskeletal disorders.
Photo Credit: Getty Images/Science Photo Library RF
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